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Among the ED visitors, the surviving cases totalled only 8,889.
Corticosteroids therapy was given in a range of 2 17 days in the death cases and 1 5 days in the surviving cases.
Sixteen (27%) of the surviving cases and 4 (2.6%) of the surviving controls who were judged non-demented at admission were demented three months after admission.
Antiviral drugs were given in a range of 1 11 days in the death cases and 2 11 days in the surviving cases.
Four per cent of the death cases and 24% of the surviving cases took the antiviral drugs no more than 3 days.
In conclusion, AR-RTD is not a uniformly fatal disease, although all of the surviving cases subsequently developed chronic kidney disease.
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However, high death rate, fulminant clinical course, laboratory verification for the surviving case, and clinical symptoms were consistent with plague.
The first 5 case-patients were initially treated for bacterial meningitis, but the discovery of Aspergillus during the post-mortem examination of the index case-patient led to the use of amphotericin B and voriconazole in the surviving case-patients (12 ).
In the 26 surviving cases the CK value rapidly decreased to below 1000 u/L.
The disability index in 1996 was significantly higher in those who died before the last measurement in 2002 using the 1273 surviving cases and 433 deaths (Mann-Whitney's U Test, P < 0.001).
Conditions among the 10 surviving cases included chronic renal insufficiency, obesity, congenital thoracic deformity, and chronic obstructive pulmonary disease (one each); asthma (n=2); diabetes (n=3); and diabetes, obesity, and chronic renal insufficiency (n=1).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com