The vitreous substitutes available to date do not provide a perfect endotamponade effect due to the physical characteristics of the available agents or the risk of damaging the retinal physiology, especially in myopic eyes.
Without a solid understanding of the value delivered (what the product can do for me), responses drift toward the price of substitutes available today.
Although there are numerous different substitutes available, the clinical evidence of the mechanical stability of these new materials is sparse.
But the phenomenon is especially pronounced when there are few good substitutes available for the product or service on offer.
Autologous bone grafts display excellent biological properties – osteoconductivity [ 7, 8], osteoinductivity [ 9], and potentially osteogenicity [ 10],- plus favorable biomechanical characteristics [ 11], and are considered the gold standard despite the abundance of allogenic and synthetic substitutes available [ 12].
The move did not go down well with his team-mates – Bayer had only four substitutes available – and the dispute threatens to overshadow Bayer's excellent run in the league, where they are on course for a Champions League place.
Other synthetic skin substitutes available in the market are Integra®, Apligraft®, Matriderm®, Orcel®, Hyalomatrix® and Renoskin®.
Nowadays, there is a wide assortment of sugar substitutes available on the market.
But, Cotterill still had to contend with a depleted squad for the majority of the season - even playing some games with only four substitutes available.
With such a substantial number of skin substitutes available for promoting healing of burns, plastic surgeons should understand the benefits and pitfalls of each, in order to help guide effective treatment.
