Given that approximately 10% of all pregnant women receive sGC in late gestation to mature the fetal lung, the present study has substantial relevance to clinical practice.
Despite the fact that findings from general population based studies on the influence of neighborhood on offending carry substantial relevance, one may question the generalizability to specific offender subgroups, such as children with a first police contact.
These results clearly demonstrate that certain M6P-bearing factors are of substantial relevance for the extent of SCC-VII invasiveness.
This protein, the mitochondrial superoxide dismutase, has substantial relevance in stress oxidative pathways and in cytokine-related diseases, such as OA [ 54].
Nonetheless, the findings of this historical cohort of U.S. workers may have substantial relevance for contemporary workers, both in the United States and abroad.
The biological plausibility of air pollution (specifically fine particulate matter) affecting health has been discussed by Pope and Dockery (2006), focusing on exposure effects on blood pressure (Brook 2008) and the cardiovascular system (Brook 2008), aspects of substantial relevance to health during pregnancy (Yoder et al. 2009).
Fourth, recent research demonstrated the importance of habit strength and implicit associations [ 10] indicating substantial relevance of positive implicit associations to strengthen the habit strength health behavior relationship.
As 3-T MRI systems are increasingly being used in a clinical routine setting and multi-centre treatment trials, this higher lesion load of cortical lesions at 3 T and the substantial clinical relevance of cortical lesions are good arguments when considering cortical lesions for future imaging and diagnostic criteria.
In dose fractionated radiotherapy the effect of different fractionation schedules could have substantial relevance in clinical practice.
Our findings are of substantial relevance for clinical trials in MS, particularly regarding the possibility that ICV transplanted BMSCs entering the inflamed central nervous system may exhibit – under conditions – a local pathology of yet unknown consequences.
