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An important aspect of the application of proteomics to the identification of disease biomarkers pertains to the substantial need for informatics resources.
Findings from this phase II study did not allow for the identification of a safe and effective dose or a regimen for further development of belatacept fulfilling the substantial need for nonnephrotoxic immunosuppressive therapy in LT recipients.
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In addition, Ms. Bellamy said, the substantial needs of children who have remained inside Kosovo, and in Serbia and Montenegro, will need to be addressed once conditions permit the return of international relief agencies to the area.
However, given the substantial needs of the families and children with asthma in this community, which already had one of the highest asthma rates in the country, we felt this effort was critically important.
Overall, the application of tissues for heavy-metal bio-assays is compromised by inconsistent intra-colony variation, and the substantial material needed to represent tissue-biomass.
Despite the many antimicrobial and chemotherapeutic agents are available in market, the emergence of old and new antibiotic resistant bacterial species in the last decade lead to a substantial need for the discovery of new classes of antimicrobial compounds [1].
In HCC and BTC, recent studies on systemic drug therapy produced the first considerable progress in medical treatment for these neoplasms for the past 30 years, but there remains a substantial need for the improvement of treatment results.
Although the figure obtained in this survey is likely to be an underestimate of the true alcohol-related burden in hospitals, the results demonstrate a substantial need for tailored interventions at ERs.
She said the proposals would maintain services "to people in the categories of critical and substantial need".
There is a substantial need for the reliable estimation of state variables, especially when they are used in the synthesis of model-based controllers or for process-monitoring purposes (see e.g. [1, 2]).
Hence, there continues to be a substantial need for the further identification of potential biomarkers whose predictive value or clinical implementation characteristics could aid current efforts to diagnose and treat alcohol abuse and dependence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com