Sentence examples for the substantial difficulty of from inspiring English sources

We use some approaches to prove the global existence-boundedness of classical solutions and overcome the substantial difficulty of the existence of a nonlinear prey-taxis term.

These results show the substantial difficulty associated with the aim of searching for all published cases.

Much of the problem arises from the substantial difficulties that media faces in China.

Initial experience revealed substantial difficulties of the students to handle the amount and complexity of the results of the CGA.

But, he said, 10percentt of the patients had substantial difficulty acknowledging the nature and severity of their disease, a problem that could call their decision-making capacity into question.

All (four) patients in the 2100-mg cohadt had substantial difficulty with the capsule load (seven capsules of 300 mg BID).

Note that the gradient term in the right-hand side of (1.1) will bring substantial difficulty to the research.

However, considering the closed nature of the position, White faces substantial difficulties in the realisation of this nominal advantage".

At 2100 mg BID grade 3 anorexia and a combination of grade 3 anorexia and fatigue yielded protocol-defined DLT in two patients, but because of substantial difficulty with capsule intake experienced by all other patients at this dose, capsule load at 2100 mg BID was considered dose limiting as well, albeit not defined by protocol.

Because of deep beliefs motivating people to commit their lives in spite of substantial difficulties, we speak of a technological ideology.

Differentiating among classes of e-mail is one of the substantial technical difficulties that e-mail postage proposals face.