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If the air pollution concentration was missing for the first address, we imputed the value at the subsequent address.
If an address could not be geocoded, the preceding address was used for NO2 calculation; if the first address was missing, the subsequent address was used.
The subsequent ADDRESS (Administration of Drotrecogin alfa (activated) in Early Stage Severe Sepsis) trial included solely 'low risk' patients but was stopped early for futility [ 12].
If NOx could not be calculated because of failed geocoding of an address, we imputed the concentration from that calculated at the preceding address, or that at the subsequent address if the NOx concentration was missing for the first address.
Missing values because of missing address or missing geographical coordinates were substituted by the levels calculated for the preceding address or, when the first address was missing, for the subsequent address, giving a complete series of annual mean NO2 and NOx concentrations since 1971.
Subgroup analysis of PROWESS and the subsequent ADDRESS [ 2] study have shown that only the sickest patients (at least two organ failures or APACHE II score >25) benefit from APC. Treatment is associated with an increased risk of serious bleeding, and so the use of APC is contraindicated in patients at high risk for this complication.
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At this stage, 0's A is set to 1, while the remaining are set to the subsequent addresses.
Initially, the address input to memory group 0's A is set to 0, while the remaining 2m−1 are set to the subsequent addresses.
These microarrays enabled us to infect the target cells in a parallelized and miniaturized procedure without significant cross-contamination: Viruses were reversibly immobilized in spots in such a way that the seeded cells were confined to the area of the viral spots, thus simplifying the subsequent addressing of genetically modified cells for analysis.
The subsequent sections address the creation and testing of the system, named as the Pathogen OutbReak PreventiOn Instruction SystEm PORPOISEE).
This section and the subsequent sections address this issue by first assuming a fixed structure analysis and later, a changing structure analysis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com