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The study is powered to detect a difference in HbA1c of 0.3 units between the groups.
The study is powered to detect a 20% decrease in triglycerides with the lifestyle intervention and an additional 20% improvement with the addition of niacin and/or fenofibrate.
The study is powered to detect a 10% difference in the number of children overweight (BMI > 85%) at 24 months.
A well-calibrated score could lead to the inclusion of a patient population with the mortality to which the study is powered (prognostic enrichment), something that has been an issue in many investigational trials [18 20].
The instruction manual made clear definitions for all data collection; for example, a sample size calculation was defined as describing, for the primary outcome, a p value (alpha), power (1-beta), and minimally important difference (the difference between groups that the study is powered to detect).
The study is powered based on the primary outcome.
The study is powered to detect relatively large effect sizes.
The study is powered to detect a 50% reduction at a 0.8 power.
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The primary pain regulatory measure for which the study was powered is temporal summation (TS), which approximates ascending pain facilitation.
The study was powered a priori, for the primary endpoint.
The study was powered to detect a 40% reduction in relative risk of POAF.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com