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Because of this, the study has implemented a sample size re-estimation, which will occur 1 year later after the 400th patient has been enrolled or once 2000 patients have been enrolled.
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Seventy-seven percent of the health centers in the study had implemented PBF by 2006; by 2007, all the health centers had either phase 1 or phase 2 PBF.
After 2000, when all countries included in the study had implemented the Hib vaccine into their national immunization programs, 7,211 H. influenzae cases occurred, including 2,005 (27.8%) Hib and 3,172 (44.0%) ncHi cases.
To our knowledge, the present study has implemented this approach for the first time, modeling how learning, as described by a RW model, modulates the effective connectivity, as assessed by a DCM, between primary auditory and visual areas.
The three small-scale areas in this study had implemented Neighbourhood Watch programs.
Previously published reports from the PREVEND study have implemented similar design-based analyses [20], [21].
As important, results will be more compelling if the ongoing studies have implemented successful strategies to ensure complete or near-complete follow-up and have paid careful attention to decisions regarding medical prophylaxis and optimising adherence in both arms of the study.
This is partly due to rapid advances in non-invasive methodologies to study brain structure and function that have outpaced data collection; it is rare that any two studies have implemented the same methods.
Similarly, recent studies have implemented NOS in the heat-stress response of A. pallida [11] and the hard coral Madracis mirabilis [13].
It is worth noting that no studies have implemented wavelet networks in regional ionospheric modeling and prediction.
Studies have implemented methods to prevent sequencing of host contamination.
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