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Results of the study could not be objectively validated; however, findings are similar to previous descriptive studies which did include objective validation.
A further 11 patients had to be removed as the data could not be validated, leaving the study population as 61,432.
In our study, 3.2% (157) of the SNPs could not be validated and were considered false-positive.
However, the accuracy of the reports themselves could not be validated.
As a result some of the results could not be validated through statistical analysis.
The CLDs could not be validated, and therefore may reflect inaccurate linkages.
We excluded 14 patients because the diagnosis could not be validated in the DCR.
As such, the GIR5.1 QTL could not be validated with the available genetic material.
However, the expression pattern could not be validated for this NIP-1 homologue.
The main limitation of this study is that performance evaluation measures could not be validated in the study.
Particularly for the earlier studies, the prognostic impact of GEP signatures could not be validated in large, external data sets (Subramanian and Simon, 2010).
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CEO of Professional Science Editing for Scientists @ prosciediting.com