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SA & LB carried out the study and conceived of the study.
AMC participated in CpG island annotation and analysis, participated in the design and analysis of the study, and conceived of the study.
EL participated in the analytical design of the study and conceived of, developed code, and drafted the methods section describing the integrative sparse k-means clustering algorithm.
Lee H managed the data and wrote the manuscript, Cha JW helped with statistical analysis, Burton RL carried out the immunoassays, Nahm MH participated in the preparation of the manuscript, and Kim KH participated in the design of the study and conceived of the study.
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M-HH participated in the study design and conceived of the study.
H-CW participated in the study design and conceived of the study, involved in statistical analysis and interpretation.
VM participated in the design of the study, in study coordinations and conceived of the study.
HD carried out the echographic and manometric studies, and conceived of the study.
IC and RDL carried out the clinical study of the patient and conceived of the study.
L-JQ and HG designed the study, and HG conceived of the study and revised the manuscript.
KI wrote the manuscript and conceived of the study.
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