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Mismatches in an organizational design are problematic.
The study design was simple.
Quality assessment (QA) of the included studies was problematic as there is no 'gold standard' design for studies of clinician patient alliance or interaction.
There are complications in this kind of study; like any human study it's problematic.
Once the inclusion criteria for study design had been defined, applying them was problematic.
A retrospective cohort study design was used.
A multi-stage study design was adopted.
So the book was problematic.
Such studies would, however, be problematic.
The service design model identified in this study is problematic.
This decision was problematic.
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