Sentence examples for the structure of mutation from inspiring English sources

Also with the upcoming naturalization of next-generation sequencing technologies, multigenic causes of disease will probably be revealed and the structure of Mutation Databases is being prepared for that.

Gene conversion appears to have influenced the structure of mutations observed in both lineages, in one case, resulting in the inactivation of a putative master gene.

Further analyses on the structure of novel RT mutation clusters will provide physic-theory of the resistance.

An exploratory data analysis (EDA) methodology was used to extract meaningful data, and the structure of the environmental mutation data was identified through mutagenesis cluster analysis, which used the K-means algorithm to classify specimens that had undergone ecological mutations into clusters [ 16].

Line 7 specifies that each attempt involves only a single mutation, though again the structure of Stylus allows simultaneous mutations conforming to any frequency distribution.

Mapping of the location of this mutation on the structure of MtbHadAB reveals that the mutation is located at the N-terminal end of αHD and lies at the bottom of the flavonoid binding pocket (Fig. 6C).

This "pathway" interaction is distinct from the statistical use of the term to define epistatic interaction, which is defined in the context of a particular phenotype and can be tested by looking at the correlation structure of mutations conditional on a phenotypic outcome (case vs. control for example).

We will focus our study on some key parameters responsible for the structure of the catalytic network: mutation rates, autocatalytic and cross-catalytic interactions.

In order to study the structural consequences of the Jak3 mutations, the structure of the human Jak3 kinase and pseudokinase domains was modeled.

The disruption of these interactions by the presence of Lys504 in the mutant (ALDH2 ∗ 2) perturbs the structure of the subunit with the mutation as well as its dimer partner [ 23].

In the case presented here, the structure of the deep intronic 44i mutation and resulting PE44.1 aberrant splicing presents a unique and valuable opportunity to apply exon-skipping therapeutics to bypass DYSF pathogenic mutations.