Sentence examples for the structure of linkage from inspiring English sources

The structure of linkage disequilibrium is approached through review of the statistical measures of allelic associations and their relationship to observed haplotypes.

We also explored the possibility that failure to replicate individual SNPs could arise due to differences in the structure of linkage disequilibrium between discovery and replication subject groups as has been suggested by some investigators [11].

We will consider the utility of trans-ethnic meta-analysis for fine mapping by leveraging the differences in the structure of linkage disequilibrium between diverse populations.

Furthermore, traditional genotyping platforms used in GWAS have primarily been designed to capture common SNPs, taking advantage of the structure of linkage disequilibrium throughout the genome, but offer only poor coverage of rare genetic variation [ 10].

Our limited knowledge of transcriptional regulation and the structure of linkage disequilibrium may in part be responsible for the lack of reproducibility of many genetic association studies in sepsis.

The structure of linkage disequilibrium (see Supplemental Material, Figure S1) and haplotypes (see Supplemental Material, Figure S2) in the 200-kb window centered on rs2325934 were constructed using the imputed genotype data of the discovery sample.

More detailed description of the structure of homeologous linkage groups, with the addition of numerous additional loci, and sequencing of large BAC fragments mapping to these linkage groups, both in duplicated and apparently not duplicated regions, could be a useful step towards the understanding of the evolution of a tetraploidized genome.

We want to calculate the probability of Li,t = 1 for all combinations of i and t, given the structure of functional linkage graphs constructed above, and the category features that the protein i has, and all the assignments of GO terms to the other proteins.

Comparative mapping with Chinook salmon permitted inference of the structure of coho linkage groups.

The data used in this paper did not have the structure of a linkage mapping study, and thus QTL genotypes could not be inferred with high accuracy.

For further information on equivalent IBD-sharing structures consider Appendix A. Our primary goal with this paper is to, in such a generally accessible way as possible, formalize and discuss the structure of nonparametric linkage score functions.