Sentence examples for the structural determination from inspiring English sources
After the structural determination of NavRh, we modeled the structure of eukaryotic Nav channels by mutating the Ser residues at the constriction site in NavRh to form a DEKA motif.
This narrow specificity of the FDL hexosaminidases has potential to be utilized in the structural determination of the biantennary N-glycan structures by specifically removing terminal α1,3-arm N-acetylglucosamine.
Since the structural determination of caspase-1, approximately 170 caspase structures have been deposited in the Protein Data Bank (PDB [ 8], www.rcsb.org) with around 30 of them assumed to be unique (<90% sequence identity).
Although single crystal X-ray diffraction has been considered as the golden standard in structure determination, we successfully used X-ray powder diffraction data in the structural determination of new synthesized compounds, in order to overcome the bottle-neck due to the difficulties experienced in harvesting good quality single crystals of the compounds.
performed the structural determination.
carried out the structural determination and refinement.
We have also determined that the structural determinations of substrate specificity are both indirect and subtle: a Pro/Ala substitution appears to be the major determination of specificity.
It is worth noting that the MALDI-TOF oligosaccharide profiles do not allow the unequivocal structural determination of the released oligosaccharides, essentially because of the isobaric nature of Xyl p and Ara f.
An important breakthrough was recently reported with the first structural determination of the WRKY domain bound to its W Box cis-acting element [ 4].
For example, the sequential resonance assignments from the Nuclear Overhauser Effect NOEE) data may become efficient and more accurate if the information on the nucleotide spatial proximity from the predicted (low-resolution) structure is combined with for the NMR structural determination of RNA.
From 2D image analysis, the 60S subunit and Sdo1p could form stable 60S-60S dimers, which should enable the 3D structural determination of dimers by single particle analysis.
