Sentence examples for the strong alteration from inspiring English sources

Only pollen dispersal was considered as a pathway with a profound impact potential, while other pathways were regarded as being less relevant due to spatially and temporarily limited GMO release and the strong alteration (e.g. decomposition) of GMO material in dung, manure or sewage sludge.

The interaction is also reflected in the strong alteration of the expression levels of the MICOS subunits in cells deficient in Aim24, most of them being up-regulated.

Furthermore, immunohistochemical score analysis confirmed the strong alteration of ZO-1 and occludin distribution and expression as compared to wild-type mice (fig 2E,H).

However, the modest changes of liver Ppara mRNA levels are unlikely to cause the strong alterations in Ppara targets (compare for instance to Fgf21, a functional Ppara target [ 25]).

We focused subsequent analyses on the cpi1-1 mutant, because it displays the strongest alteration in sterol composition of known sterol biosynthesis mutants (Men et al, 2008) and revealed KNOLLE mis-localization at the lateral PM in 43% of late cytokinetic cells.

However only two of the variants in the mature miRNA sequences exhibit a strong alteration in the in vitro functional assays that measure a subset of miRNA function; the in vitro function in two other variants with alterations in the pre-miRNA is also affected.

Furthermore, rules leading to gene order conservation may be associated to chromosome organization and distribution in the cell, as shown by strong alteration of the bacterial growth observed upon some genome minimization attempts [ 31].

The lack of a strong alteration in transcript abundance for other AtPHT1 genes in the roots of the Atpht1 8 mutant under Pi deficiency was a further indication that the disruption of AtPHT1 8 function was directly responsible for the lower capacity for Pi translocation to the shoot in this mutant.

Indeed, the lack of Tissue Factor directly affects the concentration of active factor IX, which results in a strong alteration of the CT with respect to physiological conditions.

However, we note that all conditions with diminished p18 formation are characterized by a strong alteration in the p43-FLIP to p43/p41 ratio at the DISC.

On the contrary, by exposure to pristine CeO2 nanoparticles used as the reference material in the same conditions, cells underwent a strong alteration of gene expression, with 1,643 significantly differentially expressed genes.