A softer mechanical environment enhances chondrogenesis of MSCs, evident by greater gene and protein expression of chondrogenic markers including SOX9, collagen type II, and aggrecan by inhibiting stress fiber formation, as compared to the stiffer environment.
"Everybody arrived with their sleeping bags on Friday night," she says, "which was turmoil, and then they managed to extend the conference into the Oxford Union, an extraordinarily stiff environment that was meant to produce male orators who would become prime ministers.
This work considers the control of a manipulator with the aim of executing desired time-varying motion force trajectories in the presence of a stiff environment.
While a stiff environment favored high progesterone and androgen secretion, decreasing alginate stiffness resulted in estrogen production which exceeded progesterone and androgen accumulation.
It creates a vicious cycle wherein an already stiff environment attracts and activates fibroblasts.
This highlights the advantages of analog haptics in tasks involving the display of highly stiff environments.
In this unfortunate event, CMs in the vicinity of the scar tissue sense a stiffer environment, compared to the healthy adult heart (Jacot et al., 2010).
The foot-terrain interaction is usually tackled by disregarding some of the effects of ground deformation, like permanent deformation and compaction; however this approach restricts their application to stiff environments.
In a stiffer environment, the fibroblasts will transdifferentiate and start to express αSMA and secrete ECM proteins.
We have previously shown that in mouse embryonic fibroblasts, particles located in a cell's lamellar region probe a stiffer environment than that of the perinuclear region, suggesting that lamellar particles are entangled in an actin network higher in density compared to that of the perinuclear region.
