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Yet the statistical implementation of the framework is robust to data noise and outliers.
In that case the choice of the statistical implementation should depend on other factors, such as speed and desired flexibility.
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Finally, comparison with experimental data sets including indirect protein-protein interactions [ 75- 77] is made by adopting a statistical implementation of the "combinatorial logic" discussed above (see Supporting Information).
The effects of projectile characteristics on the probabilistic impact response of single-layer fully-clamped flexible woven fabrics is numerically studied using a yarn-level fabric model with a statistical implementation of yarn strengths.
The focus of the course is on stochastic methods suitable for real time analysis and their statistical implementations.
The authors would like to thank Karen Meyer-Arendt for work on the Statistical Coupling Analysis implementation, Micah Hamady for work on the Myosin alignment, and Massimo Buvoli for suggesting the Myosin rod domain as a subject for coevolutionary analysis.
Although the statistical details of the implementation of the process can be found in GAP's background documentation note, it is based on state-space models, where parameters are estimated by exact maximum likelihood and the Kalman filter is used to generate the unobserved variables.
DC participated in the design of the study, conducted the statistical sampling, supervised study implementation, performed data analysis, and drafted the manuscript.
The statistical analyses of this implementation trial were primarily descriptive, using counts, percentages, means and standard deviations, medians and interquartile ranges, and 95% confidence intervals.
The remainder of this paper is structured as follows: the example dataset is first described followed by a Methods section describing the statistical models developed and implementation of the models.
SYW developed the analysis plan and carried out both the statistical analyses and software implementations under the close supervision of HG and JCT.
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