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Forced degradation experiments were also performed to evaluate the stability and specificity of the proposed HPLC method in different mediums.
Most progress in computational design of protein self-assembly has focused on α-helical systems, exploring ways to concurrently optimize the stability and specificity of a target state.
Previously, numerous studies have attempted to identify the factors that determine the stability and specificity of SSE associations through analysis of super-secondary structure model systems like β-sheets and coiled-coils.
Native interactions contribute to the stability and specificity of a complex, whereas nonnative interactions mainly perturb the binding kinetics.
However, changes in the shape of the DNA reduce the off-rate of the proteins which greatly enhances the stability and specificity of ternary complexes compared to binary ones.
Structural and biochemical data indicate that water-mediated interactions are important for the stability and specificity of recognition, despite the fact that interface solvent molecules exchange rapidly with the bulk solvent [36].
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In this way, the sensor coupled the high stability and specificity of LNA with the unique electrical properties of carbon nanotubes (high surface area, fast heterogeneous electron transfer, chemical stability, and ease of miniaturisation).
Conjugation of biomacromolecules like proteins on to the hydrophilic iron oxide nanoparticles, improves the colloidal stability and specificity of the system [49, 50, 51].
The unique stability and specificity of the DEPMPO O2 – spin trapping method makes it applicable to complex biochemical systems such as XO and XDH.
The results further confirm the superiority of the PMO support compared to MCF and also reveal that the different immobilization protocols strongly influence the activity, stability and specificity of immobilized TLL.
Soils are continuously exposed to large amounts of engineered nanoparticles, especially silver nanoparticles (AgNPs), which can affect the activity, stability, and specificity of microbial enzymes.
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