Sentence examples for the specific checkpoint from inspiring English sources

The specific checkpoint proteins that regulate cell-cycle progression in response to lipolysis are currently unknown.

The specific checkpoint-monitoring availability of lipolysis products is unknown.

Analysis of the oocyte transcriptome during maturation using global mRNA analysis techniques provides a resource that can be mined and expanded continuously with new software and sequencing techniques to identify genes involved in the processes of meiotic and cytoplasmic oocyte maturation and the specific checkpoints regulating acquisition of full competence [ 32].

Some reports suggest that the ATM and ATR kinases target specific checkpoint components depending on the genomic lesion identified, while others suggest that it is not in fact lesion recognition, but the processing of diverse lesions by distinct DNA repair factors which ultimately recruits and activates particular checkpoint components [43], [44].

Together, these data underline the notion that hepatic TSC22D4 fulfils a critical and specific checkpoint function for the regulation of circulating VLDL-TG and hepatic TG load, and that high TSC22D4 levels induce serum TG depletion and hypobetalipoproteinemia under both normal and high caloric intake conditions.

Lesions in DNA can occur throughout the cell cycle, and are sensed by specific checkpoint pathways in interphase [3].

With our increasing knowledge of cell cycle regulation, many compounds have been developed to inhibit specific checkpoint components, particularly at the G2/M transition.

Voynova, E. et al. Requirement for CD40/CD40L interactions for development of autoimmunity differs depending on specific checkpoint and costimulatory pathways.

Both p21 and p27 are specific checkpoint proteins for G1→S phase transition and are significantly up-regulated in NSPCs grown in CM from BV2 JEV) compared to CM from BV2(C) (Fig. 7B, C) (p<0.05).

We anticipate that an unbiased genetic screen to identify such factors that can support survival when Chk1D469G is present in single copy may reveal additional mediators that contribute to damage specific checkpoint responses.

Cell cycle was examined using flow cytometric analysis, RT-PCR, and western blot analysis of specific checkpoint regulators.