Sentence examples for the source of this bottleneck from inspiring English sources

The source of this bottleneck is likely mediated by multiple physical and immunologic factors that limit which virus particles can reach the genital tract, penetrate the mucosal barrier, productively infect target cells, and then traffic out of the mucosa for systemic dissemination the sum total of which effectively blocks transmission in >99% of unprotected sexual exposures (8, 9).

Several approaches have been used to improve the utility of such systems, depending on the source of the bottleneck, including mutagenesis of ncAA-RS active-site amino acids, optimization of the suppressor tRNA recognition, modification of RS proof-reading domains, replacement of endogenous tRNA/RS pairs, modification of elongation factors, and reassignment of chromosomal amber codons.

"What is the source of this?

What is the source of this power?

What is the source of this faith?

The source of this great wealth?

The source of this precipitation remains unknown.

What is the source of this reaction?

Find the source of this rudeness.

One potential source of this bottleneck is the unique environment of the male and female genital tracts, which may feature different target cell populations from those the majority of viruses face in systemic infection.

We investigated the source of the animals' bottleneck at the mechanistic level.