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The biologists are also getting historical, partly prompted by April's 50th anniversary of the solution of the structure of DNA.
The solution of the structure of the photosynthetic reaction center from the bacterium Rhodopseudomonas viridis is described, and the structure of this membrane protein complex is correlated with its function as a light-driven electron pump across the photosynthetic membrane.
We propose a novel approach for predicting forces in a structure after altering physical properties of some of its elements (new structure) using the solution of the structure before any change (parent structure).
Nevertheless, a rather simple model of a frustrated chain packing could be improved by Fourier methods even though the solution of the structure by direct methods was itself frustrated by the extensive overlap of |Fhk0| and |Fkh0| or |Fhkℓ| and |Fhk,−ℓ| amplitudes which led initially to a false prediction of space group symmetry.
They were first visualized by crystallography in 2006, following the solution of the structure of a bacterial peripheral arm from Thermus thermophilus [11].
We believed that the solution of the structure of the complex of Evasin-1 with CCL3 would reveal the reason for the surprising selectivity of the former for the latter.
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Examples include the solution of the protein structure of hemoglobin, molecular cloning of the globin genes, the first human disease solved at the molecular level (sickle cell disease), key insights into protein quality control, and the recent discovery of water channels in red cells, which was awarded the Nobel prize in Chemistry.
Elucidating how NUC-1 acts more actively than CRN-6 and CRN-7 awaits the solution of the 3D structure of each DNase II.
Especially ligand-based NMR experiments that are far less demanding than the solution of the whole complex structure are helpful.
Direct multiple-wavelength anomalous diffraction phase information was used for the solution of the T282C EtHg-derivatized structure.
The pace of research in ICL has increased ever since the solution of the MTB ICL crystal structure [ 5] in 2000.
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