It charges online students the smallest amount necessary to cover its costs.
"We should be working toward the smallest footprint necessary, a presence that puts Afghans in charge and presses them to step up to that task," Mr. Kerry, the chairman of the Senate Foreign Relations Committee, said at a hearing.
In this case, the driving engine behind science has been its reliance on reductionism, which means breaking a hard problem down into the smallest part necessary to make it easier to solve.
A promising approach in recent studies has been the integration of over 100 kb sized BAC constructs to delineate the smallest regions necessary for silencing or escape.
Consistently, the region encompassing the LRR and part of the C-terminus (residues 302 668) has been defined as the smallest region necessary and sufficient for the association of yCCR4 with yPOP2 [ 11].
The MDC95 is the smallest change necessary to exceed the measurement error of repeated measures that indicates a real change at the 95%% confidence interval (CI) level for a single individual [ 38, 39].
Most importantly, such approach helps to create the smallest cavity necessary to remove all the cholesteatomas so as to preserve more external auditory canal (EAC) bone to facilitate reconstruction.
On the basis of all available data, a specific binding region for each of the three cell wall components (rSbsC, SCWP, and peptidoglycan) could be identified in the C-terminal part of the rHMMA, representing the smallest regions necessary for interaction (Ferner-Ortner-Bleckmann et al., 2009).
Consequently, the description of a metastable orthorhombic Ta2O5 structure, with lattice parameters of a = 6.425 Å, b = 3.769 Å and c = 7.706 Å, is ideal for materials without long-range ordering (and the thereby missing formation of a superstructure) as well as for detailed atomistic studies, owing to the much smaller necessary cell sizes.
More direct evidence showing that endogenous ROS production is necessary for induction of the HS response comes from the observation that a dominant negative allele of Rac1, the small GTPase necessary for the activation of ROS production by membrane-bound NADPH oxidase [ 61], inhibits the stress-induced activation of Hsf1 [ 62].
