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Perhaps less consistent with the intention was the sizeable change between the preoperative Charnley class and the class 1 year later.
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This is a much more sizeable change in the treatment effect estimate, implying a larger quantity of underlying residual confounding biasing the estimate away from the null.
Of these patients, 2,749 were from class A and 407 were from class B. While this resulted in a sizeable change between classes, the regression models did not improve from application of this knowledge; both the EQ-5D index and EQ VAS had poorer BIC with the split B class.
In view of the sizeable climate change challenge, we need a clean innovation machine operating at full speed.
"If there were to be a reasonably sizeable change [by regulators] then you would probably see a change from some of the players in the UK market.
Pakistani women had lower RRs with no sizeable change on adjustment.
Any Mixed background females had a higher RR with no sizeable change on adjustment.
One possible reason for this is that altered splicing of exon 2 would be 'shared' across four tau protein isoforms (1N3R, 1N4R, 2N3R and 2N4R), thus a sizeable change would be needed to allow detection by a semi-quantitative technique such as western blotting.
During the past decade, QQ has managed to withstand and cement its position in the digital communications sector in spite of sizeable changes and developments in the Internet landscape and associated technologies.
Analyses of cyclonic activity over Central Asia do not show sizeable changes in the total cyclone numbers, and there are some increases in their variability.
There are sizeable changes in the composition of inflows from expansion to recession, with workers becoming on average younger and less educated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com