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No specific value can be provided for the size of modification indices warranting attention but in practice a reasonable value can be obtained by remembering that only about three model modifications can reasonably be made to a model [ 27 ].
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The size of a modification index should be considered with respect to other modification indices and also the magnitude of the chi-square statistic [ 24].
Histone ubiquitylation represents a particularly intriguing PTM given that the size of the modification (76 amino acids) rivals the size of the histone substrate.
The size of this modification is small compared to the size of the insulin molecule and should not change its binding characteristics, the effect on receptor phosphorylation, the rate of nonspecific insulin binding or the rate of renal insulin filtration.
To quantify the size of the loan modification safety net and its changes over time, I estimate the amounts that "home retention actions" (as the federal government calls these mortgage modifications that allows people to stay in their homes) actually changed mortgage payments from the original mortgage contract, which specified only payment in full or foreclosure.
The second issue is whether double-stranded donor DNA can be used when the size of the desired modification precludes the use of oligos.
It is also well known that the presence, direction, and size of modification can be dependent on the choice of measure [ 50].
TcTS was used to transfer these structures to an isolactoside, and Michaelis constants of the donors indicated the kind and size of modifications allowed at the 5-nitrogen site.
The attempts to improve the fit by varying the size of the particles and modifications of the dielectric functions were not successive.
Because the size of proteome before post-translational modifications is still unknown, we use the size of complete transcriptome instead.
Besides the above modifications, the size of cyclic peptide ring [ 30], the length of N-terminal linear tripeptide segment [ 31], and the generation of mimetic compounds [ 32] are also involved in polymyxin modification.
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