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The shared reaction is then a reaction junction.
We found that the shared reaction sets, obtained when decreasing the number of organisms, range from zero to five and the mean varies from 0.2 to 2.5.
A reaction junction occurs, when two paths share a reaction (r3 in Figure 5) but the reactions preceding the shared reaction (r1, r2) do not share any product metabolites.
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The shared reactions are involved in metabolic pathways that are also included in the minimal metabolism described by [ 8, 21], such as glycolysis and nucleotide biosynthesis.
The only shared reaction is not assigned to participate in any metabolic pathway in MetaCyc.
While such shared reaction to the comic buffeting of obvious targets may contribute to an atmosphere of pleasure, the show as a whole remains uneven.
This model described well the decay of shared reactions in the INTRA group.
This raised the question whether, as we add organisms, the decay of shared reactions and its limit was the same in these groups.
Finally, by using simulation, we tested whether the decay of shared reactions and its limit would be the same for cell-associated and extracellular bacteria as for the intracellular ones.
The reaction similarity between any two models is calculated using the following formula, (8) Similarity = A 2 A + B A + C A denotes the total number of shared reactions between the two organisms, whereas B and C represent the number of unique reactions in each model.
These bacteria had a weak impact on the number of shared reactions, while they had a strong effect on the common partial EC number set.
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