For each level of receptor, we compared results based upon the "sharing" docking model with results generated using a "competing" docking model.
Simulation results in Figure 5A-B are intriguing in that they predict that the capability for "shared" docking does not significantly affect overall recruitment of adaptors, even in simulations using high density of receptors (either through clustering or overexpression).
The integrity of phosphorylation events of specific MPK with their substrate proteins is mediated by shared docking domains and adaptor proteins [ 1, 5].
Using the T530D variant, we then tested whether Sirt1 activation through Thr phosphorylation and by resveratrol exploit a common mechanism, such as a shared docking site or conformational change, or whether they are additive.
At the shoreline, there's a shared dock with a slip deeded to the house.
This spring, a two-year-old, three-bedroom, three-bathroom house on a golf course with a shared dock on the lake was going for $535,000.
The property has deeded water access, mooring and a shared dock.
It sits on a sheltered inlet with direct access to the ocean, and they launch their kayaks from a shared dock.
Full season (Memorial Day through Labor Day): $30,000, with shared dock, or $40,000 with exclusive dock.
Nuon Chea and Khieu Samphan, who both face an upcoming genocide trial, originally shared the dock with Khmer Rouge foreign minister Ieng Sary, who died in March, and his wife Ieng Thirith, the social affairs minister, who has dementia and was declared unfit for trial in 2012.
