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To investigate whether favipiravir treatment in vivo resulted in the selection of adapted MNV-3 variants, we carried out infections in RAW264.7 cells with virus samples recovered from mice.
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We propose that environmental changes play a direct, active role in the evolution of genomes by inducing genetic variability, thus allowing the selection of more adapted genotypes along with their more adaptive stress response.
Moreover, the selection of suitable adapted microbial biogas biocenoses deserves intensified studies.
The ultimate goal of developing such models is to provide a new tool for predicting crop yields that will allow the selection of crops adapted to lower inputs and to particular environmental conditions, while maintaining an acceptable yield.
The massive use of drugs in medicine and of pesticides in agricultural systems since the 1950's have led to the selection of highly adapted resistant biotypes in natural populations of microbes and pests (Georghiou 1986; Guillemot 1999; D'Alessandro and Buttiens 2001; Hastings 2004; Levy and Marshall 2004).
In this manuscript we ask to what extent prior flooding affects the ability of plants to survive and regrow after mechanical disturbance, and whether different flooding regimes have led to the selection of locally adapted ecotypes that differ in their responses to fragmentation after flooding.
It was a show of lofty ambitions, with Lee and the Unthank sisters, Rachel and Becky, performing a motley selection of adapted poems, traditional music, songs of the era and original material reflecting human experiences both on the front line and at home.
These results suggest that adaptation of avian influenza viruses in land-based birds such as quail and chickens, not only can result in the selection of strains better adapted to replicate in mice but also in the selection of strains that can rapidly acquire mutations that favor replication in mammals.
For each respondent, the selection of items is adapted to the prior estimates of the construct being assessed [ 7].
The sampling frame for the selection of respondents was adapted from a similar tool developed in Canada [ 19].
This could occur through the selection of target site-adapted mutants (6) or reversibly through induced phenotypic adaptation (24).
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