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We did not detect a statistically significant deviation from predictions for either of the selected effect levels (Table 3).
As a result, most biologists use the selected effect concept of function, following the Dobzhanskyan dictum according to which biological sense can only be derived from evolutionary context.
In the analyses, beta represents the difference in mean birthweight (continuous variable) for cigarette smoking between the variant genotype after adjustment for the selected effect modifiers.
Cutoff points for elevated cholesterol levels, low birth weights, or late onset of walking in children are all derived by determining certain percentiles often the 95th percentile of cumulative population frequency distributions of the selected effect variable.
The selected effect definition of function has led to the discovery of many new functions, for example, microRNAs (Lee et al. 1993), and to the rejection of putative functions, for example, numts (Hazkani-Covo et al. 2010).
For decades, epidemiologists have used the term "effect modification" in a broad context, simply referring to a variation in the selected effect measure for the factor under study across levels of another factor [ 49].
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The selected effects are listed in Table 3 with the corresponding AICc, clearly showing that the latter is always dramatically lower than the AICc including all 19 initial effects.
The third fundamental element in this framework is that inferences are made on the basis of a selected "effect metric " that defines "toxicological equivalent" magnitudes of effect.
Thus, the second sequence has no selected effect function, but its causal role function is to bind a transcription factor.
For the HMNL and LCMNL models, we report selected effects of respondent-characteristics on the scale-parameter and latent-class membership.
Therefore, the regression curve works well to measure the neutral degree when selecting effect dominates the evolution [ 74, 75].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com