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For Michael Fury, 62, a husband may be the second most significant addition of the year.
Senator Rand Paul may have staged a Senate-shaking filibuster Wednesday, but his was actually only the second most significant Republican filibuster of the day.
The Giro d'Italia is the second most significant bike race in the world after the Tour de France – which starts in Yorkshire this year (in case you hadn't heard).
The second most significant source was the background activity.
Initial straw MC was the second most significant factor influencing strawboard quality.
The second most significant source of sulphate input is rainfall and it is characterised by a mean contribution of 30%.
Mesopores contribute the largest pore volume and specific surface area (SSA), whilst the second most significant pore size range is macropores.
Ferropenic anaemia is the second most significant nutritional disease which has spread worldwide and affects several risk groups, mainly young women and children.
The bias voltage is the second most significant factor with its percentage contribution being 24.2% on HMS and 31.0% on SpSNR.
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It may have been the second-most significant victory of Rubin's embryonic career after his victory over McEnroe, the seven-time Grand Slam tournament winner.
The captain and leading scorer for Liverpool of the English Premier League, he is arguably the second-most significant import in league history, behind David Beckham.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com