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Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell.
This series of experiments was designed to examine the second messenger system by which this occurs.
Generation of the second messenger molecule cAMP mediates a variety of cellular responses which are essential for critical cellular processes.
The second messenger was the cGMP since the analogous 125 μM 8-Br-cGMP mimickeffectseffects.
The second messenger cyclic adenosine 3′,5′-monophosphate (cAMP) regulates a wide range of physiological processes in almost all organisms.
The second messenger pathways involved in acetylcholine-induced contraction are complex, and have recently been reviewed107 (Figure 8).
Recent work indicates that biofilm formation is triggered by a drop in the levels of the second messenger cyclic-di-AMP.
The second messenger and molecular consequences of elevated adenosine may be useful in explaining "sleep debt", the long-term consequences of sleep restriction/deprivation.
The second messenger molecule cAMP, which modulates cell growth and differentiation in organisms from bacteria to higher eukaryotes, is produced by adenylyl cyclases.
Cellular levels of the second messenger cyclic di-guanosine monophosphate (c-di-GMP) are determined by the antagonistic activities of diguanylate cyclases and specific phosphodiesterases.
Dependent on the second messenger level, specific c-di-GMP receptors then control fundamental cellular processes, such as bacterial life style, biofilm formation, and cell cycle control.
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