Exact(4)
The scope of variation in cost per QALY gained reaches from cost-saving (2.5%) to less effective (<1%).
This dataset of genomes coupled with phenotype will be useful in understanding the scope of variation, but Church cautioned that the diagnostic value of genomes is limited.
Where possible, we have reported absolute values in the tables to allow readers to appreciate the scope of variation, as well as absolute differences in levels between groups.
In terms of accuracy, both the metrics based on continuous scores were seen by clinicians as limited in the scope of variation that they allowed to discern; this was not however unique to these metrics, but to the analyses, and applied equally to the categorical or dichotomous metrics.
Similar(56)
While genes delineate the scope of variations, environment applies the final touches.
The resulting CB4856 reference sequence extends and refines the scope of the variation between N2 and CB4856 from prior studies.
The advent of next-generation sequencing technologies make it possible to extend the scope of structural variation studies to a point previously unimaginable as exemplified by the 1000 Genomes Project.
Identification of allelic variants has accelerated as a result of the cataloging and mapping of single nucleotide polymorphisms (SNPs) throughout the genome by the International HapMap Project (21– 23) and characterization of the scope of structural variation, including copy number variants, in the genome (24– 24).
Thus, the failure of LI08 to appreciate the full scope of variation at Gp-9 and design assays accordingly could explain their inability to detect relevant GP-9 variation using PAGE in three of four ostensibly polygyne colonies.
Within the scope of this parameter variation, the congruency between OCP transients, potentiodynamic sweeps and time resolved dissolution profiles is discussed.
Thus, large scale efforts have been lacking to critically evaluate the role of mtDNA mutations in human disease and to investigate the scope of normal mtDNA variation in populations.
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