"The task of measuring and [building] omics data sets on this scale is considerable and effectively integrating them to describe the complexity is even greater," agrees Jeremy Nicholson, a biological chemist at Imperial College London who heads the MRC-NIHR Nationel Phenofe Centhe there, one of the world's largest high-throughput metabolic phenotyping centers.
The interannual variations in outbreak scale were considerable, ranging from 45 confirmed patients in 2004 to 766 in 2006.
While the differences between the various HRQOL scales are considerable for individual predictors, the fundamental relevance of the personality variables and the physician-patient relationship was seen to be independent of whether the SF-12, the MacNew questionnaire, or the SAQ was used.
The importance here of scale, though, is considerable, since patterns can be subject to significant heterogeneity within units of analysis: previous studies have shown area-level crime rates to be driven largely by those of only a few streets (Weisburd et al.2004) and burglary risk to vary significantly between individual houses (Bowers et al.2005).2005
The challenges in the scale-up were considerable, especially to achieve uniform quality of the product.
The western Kenya highlands are an area of particular interest based on the fact that on a relatively small spatial scale, there is considerable variation in altitude, water accumulation, and land-use patterns.
The results of the present simulation show that the effect of the scale layer on the slab heating is considerable.
At seasonal and decadal scales there is considerable variation in the number of events (Supplementary Fig. 8), but systematically comparing these over time is not possible because of the incomplete data coverage (Fig. 2c). Figure 5: Seasonal distribution of extreme sea level and skew surge events.
However, it is less certain if this is also true on the field scale where there is considerable uncertainty with regard to the size of effective diffusive length scales.
Within the general stability of the ecosystem, there is considerable small-scale variation in oceanography.
Available evidence indicates that the scale of this diversity is considerable, as it will be discussed in this review.
