Sentence examples for the samples ascertained from inspiring English sources

Associations between intelligence and SNPs in the ATXN1 and TRIM31 genes and in three genomic locations showed replicated association, but only in the samples ascertained for ADHD, suggesting that these genetic variants become particularly relevant to IQ on the background of a psychiatric disorder.

For one of these SNPs (rs2807822, intergenic, 14q11.2-12), however, the effect was in opposite direction in the two samples ascertained for ADHD, also indicated by a significant heterogeneity effect (P = 0.04; see Supplementary Table S2).

We first conducted a combined analysis on only the two samples ascertained for ADHD.

When we combined the two samples ascertained for ADHD (totaling 822 subjects), we found that five SNPs were associated with IQ.

We used a stepwise approach, in which we first ran a combined analysis based on the two samples ascertained for ADHD, and then conducted a meta-analysis on all 4,963 subjects.

When combining the two samples ascertained for ADHD we found that of all tested SNPs, 12 had a P-value <0.05 (same direction of effect) of which 6 showed evidence for associated after Bonferroni correction (P < 0.001) for multiple testing.

The SLIC probands were selected from samples ascertained by the Newcomen Centre at Guys Hospital and by the Manchester Language Study (The SLI Consortium, 2002) and all had severe language impairments with language skills more than 1.5 SD below the normative mean for their chronological age in combination with full IQ scores at least 0.7 SD below that expected for their age.

In this study we compared the HapMap samples with population samples ascertained according to more standard sampling protocols, using both autosomal and Y-chromosomal datasets.

Some of these estimates were generated in samples ascertained on the basis of phenotype or from special populations (such as SL and CV) (Havlik et al. 1980).

At very low IQ, the LoF rate is similar to that seen in samples ascertained for severe ID [ 19 ▪].

Phase III of the International HapMap Project (HMP3) provides a reference panel of haplotypes at approximately 1.6 million variants, genomewide, obtained from 1,184 samples ascertained from 11 populations of European, Asian, and African descent [The International HapMap Consortium, 2010].