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The sample was ascertained for developmental complexity and CNVs were rated as present if considered pathogenic (de novo or absent in controls) but psychiatric phenotype data were not available.
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Although this sample was ascertained for attention deficit/hyperactivity disorder (ADHD), intelligence quotient (IQ) scores were distributed normally.
The surface topography and the nitrided layer thickness of the samples were ascertained from optical and electron microscopy.
The quality of the DNA sample was ascertained by electrophoresis and determined to be of high quality (size >23 kb) with no visible degradation.
The most probable location for each sample was ascertained by the highest mean log-likelihood ratio of each sample's assignment across these independent runs.
All NGT participants underwent an OGTT and were classified according to WHO criteria [ 8].The third replication sample was ascertained from the Breda study (NL3) [ 11, 12].
This sample was ascertained and recruited independently from the DHS, but using the same diagnostic criteria for T2DM diagnosis and has been the basis for prior genetic studies of T2DM [ 31, 32].
One sample was ascertained for ADHD, and three samples were population-based samples.
The quality of the ligands in the final samples was ascertained by comparison of one-dimensional proton spectra of the samples to reference ligand spectra.
Of these, 1,105 participants (11.3% of the final sample) were ascertained to have incident diabetes during follow-up.
The integrity of the DNA samples was ascertained by positive amplification of human DNA ß-globin control.
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CEO of Professional Science Editing for Scientists @ prosciediting.com