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For the present study the sample size analyzed was 6,421 weighted to represent 76,509 Canadian women.
Only eight studies are eligible for our meta-analysis and the sample size analyzed in each group was relatively small.
The high degree of concordance of the data would allow to expand the NGS analysis to all archived GIST specimens, thus enlarging the sample size analyzed.
However, we do agree that reporting the actual power of the tests to detect the originally reported effect size estimate based on the sample size analyzed in the replication study is important and will be reported.
However, the sample size analyzed here (795 SCD patients), besides a less heterogeneous ethnic origin (since all patients came from the same Brazilian state, Pernambuco), confers consistency on these results.
Second, although the sample size analyzed here was larger than that in previous studies performed in Sweden and Czech Republic [ 16, 17] on the relationship between S100A12 levels and mortality in hemodialysis patients, the total number of deaths in this Japanese study was small.
Similar(54)
Considering bias, variance and mean square error criteria of estimates of parameters and quantiles, it is concluded that in general for the values of the shape parameter considered: −0.1, −0.3, and −0.5 and 0.1, 0.3 and 0.5, the sample sizes analyzed: 9 ⩽ N ⩽ 99 and non-exceedance probabilities: 0.01 ⩽ Π x) ⩽ 0.10, the ML method performed better than the other five.
The sample sizes analyzed are generally small, whereas the variation within each group is quite large, thereby reducing confidence in the conclusions.
The sample sizes analyzed are considerably smaller than those of GWAS that have successfully identified genes for other complex disorders [ 36].
The ratio of GCB to non-GCB subtypes in Chinese patients with DLBCL of PGL has not been extensively investigated and the sample sizes analyzed so far, including in our study, have been small [ 17, 18].
The extrapolation of the cutoff points proposed in the present work has the limitation of the small sample size analyzed, so it requires further research.
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