Interestingly, all 20 rhesus macaques possessed the same two copy sequences without any within-copy polymorphic sites, implying strong functional restriction.
To determine whether BRE elements confer AD localization activity onto the GLS element, we inserted the same three copies of the BRE from the oskar 3' UTR that faithfully repress oskar translation [28], [30] into the KGFP+GLS and KGFP+GLS+TLS reporter constructs.
For the exact same two copy 30-megabase region from the same human tumor sample grown in xenograft, the observed distribution of the MAF (Fig. 3D red line) is centered at 0.47, below the expected value of 0.5 (Fig. 3D blue line).
All these years, the supplemental footage tells us, we've been watching grainy copies of copies of the same two or three moments.
Using the same two turntable set-up of disco DJs, Campbell used two copies of the same record to elongate the break.
The editor didn't have to arrange every single hit, since the piece is composed very mechanically: there are two copies of the same eight claps, in 12/8 time, and one copy gets moved to the left by a single beat, creating complex rhythms.
To this aim, we constructed a series of pIRES vectors that allowed us to express under the same transcript two copies of the AGT cDNA bearing the analysed polymorphic and pathogenic mutations in different combinations (Fig. 1).
Like two copies of the same encyclopedia".
Year-on-year the UK edition was also virtually the same, up by two copies on average.
In addition, the clonally related isolates JK-31 and BQ2-D70, which represent different copies of the same original isolate, and the two copies of the Toulouse isolate included in this study (Freiburg and CIP 103739), revealed an identical allelic profile, indicating a high stability of the allelic polymorphisms detected in this study.
