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The first ATG codon within spliced CXCR3-B mRNA is the same initiating ATG of CXCR3-A (see Fig. 3A, highlighted in red).
Different lines of MIN-O mice, which were established by transplanting MIN lesions to separate hosts, have characteristic histopathology, metastatic potential, and tumor latency, suggesting that MIN lesions have different biological outcomes despite the same initiating oncogene (PyVmT) [ 11].
We hypothesize that even with the same initiating oncogene, the resulting early premalignant lesions and subsequent tumors will have different groups of biologically distinct characteristics that are determined by the genetic changes already present in the early lesions – in this case, in the MIN-Os.
Even in colorectal cancer it was shown that in cells from the same tumours, all assumed to have the same initiating loss of APC or oncogenic activation of β-catenin, dynamic localisation changes between nucleus and cytoplasm can be found (Fodde and Brabletz, 2007).
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But a long, punishing war in defense of your own country – think World War I – is hardly the same as initiating a nuclear exchange.
Fascist Italy, led by Benito Mussolini joined the pact the same year, initiating the formation of the so-called Axis between Rome, Berlin and Tokyo.
These cancer cells originate from the same clone, initiating malignant tumor cell growth capable of out-of-control proliferation.
Both ishemia and inflammation can initiate VEGF production.VEGF production can be induced by other factors and at the same time initiate a cascade of other factors.
"These are the same slogans initiated by the reformers".
They brought and commissioned work by artists such as Ian Hamilton Finlay, Anish Kapoor, Cornelia Parker and Andy Goldsworthy but at the same time initiated new attitudes to the way art can be seen.
Further, the ministry said, "The Palestinians must understand that they can't have it both ways: they can't enjoy cooperation with Israel and at the same time initiate political clashes in international fora".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com