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The u4 loop forced DNA tetrads into the same conformation as adopted by g4u4g4.
E190 has the same conformation as in other glutamate-bearing FIC protein structures (Fig. 1b) and is stabilized by a salt bridge with Arg122 and, when present, by interactions with the nucleotide cofactor (Fig. 1c).
Comparison of the PRPP binding mode in type I, II and III PRTs indicates that AnPRT does not bind PRPP, or nearby metals, in the same conformation as other PRTs.
The identification of a trisaccharide analogue that does not cross-react with Lex but still retains the same conformation as Lex constitutes the first step to the design of a safe anti-cancer vaccine based on the dimeric Lex tumor associated carbohydrate antigen.
If the ϕ1-O-C-C-N chain in template2 adopts the same conformation as that in template3, then these three templates exhibit approximately the same distance between the center of the ϕ1 benzene ring and the amine N atom.
The docking protocol predicted the same conformation as was present in the crystal structure with RMSD value close to the allowed range [48] and surrounded by the same active site residues of the enzyme.
Similar(19)
The grafted polymers took on the same conformations as the corresponding free polymers; however, the change in conformation at higher temperatures did not take place.
In the Shanghai and Anhui N9-oseltamivir carboxylate complex structures, E276 adopts the same conformations as in the uncomplexed structures.
Interestingly, one of the predicted SDPs, 783A, can cause steric obstructions, preventing binding of sildenafil to PDE4B in the same conformations as to PDE5A ([ 27], Figure 4B).
In the first, the same conformation is observed as in the crystal structure, but the arch is invisible, whereas in the second state, the most of the vRBL is invisible, suggesting its enhanced flexibility in the absence of bound vRNA.
(B ) Cryo-NS reconstruction of the short linker dynein Lis1 complex; the linker assumes the same conformation with Lis1 bound as in the absence of Lis1.
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