They need not exist in the same conformation, and conformational changes are not propagated to all subunits, thereby providing the possibility for a hybrid TR form to occur.
The X-ray structure of 4 was used a starting point in the geometry optimization of 1tr to avoid time-consuming conformational searches, and the same conformation was used in the calculations for 1tts and 1tp.
Here, I introduce a new computational approach that enforces conformational symmetry, whereby all chains in the system adopt the same conformation.
Additional data on the slight movement of the bound head upon powerstroke support the conformational change of the bound head instead of it staying in the same conformation.
The parallel coiled-coil between chains B and D and F and H holds these chains in the same conformation, whilst flanking chains A and C and E and G show wider conformational freedom.
The u4 loop forced DNA tetrads into the same conformation as adopted by g4u4g4.
In the case of the double bond sub-layer if a conformation is defined in identifier Y, the same conformation must also be defined in identifier X.
Some RNPs achieve the same conformation regardless of temperature, others show minor adjustments in 16 S rRNA conformation upon heating and, finally, others undergo significant temperature-dependent changes.
The circular dichroism (CD) spectroscopy showed that Anal R and Anal S have the same conformation of Rev NIS, with a significant fraction of helical structure.
One assumption we wanted to avoid in our docking protocol was that the same conformation of a drug would be the same 'active' conformation in the presence of peptides P1, P2, or P3.
If the ϕ1-O-C-C-N chain in template2 adopts the same conformation as that in template3, then these three templates exhibit approximately the same distance between the center of the ϕ1 benzene ring and the amine N atom.
