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The route utilizes a regio- diastereo- and enantioselective Mo-AAA to construct one of the two vicinal quaternary carbon stereocenters present in the target.
To install the second quaternary stereocenter in the target, the route utilizes a novel regio- and diastereoselective allylation of a cyclic imino ether to deliver an allylated imino ether product in near quantitative yield and with complete regio- and diastereocontrol.
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The route utilized the routing of legislative Route 15 from Hornell to Dansville and from Mount Morris to Shakers Crossing, the modern junction of NY 63 and NY 408 northeast of Mount Morris.
The route utilized part of NY 6 and NY 30, two highways assigned in 1924.
North of Romulus, the route utilized the alignment of legislative Route 36 from Romulus to Seneca Falls and modern NY 89 from a junction east of Seneca Falls to Wolcott.
In between the two locations, the route utilized modern NY 9N, Montcalm Street, NY 22, and Wrights Ferry and Wrights roads.
According to these divergences, the routes utilized by CHIKV to infect its target cells cannot be inferred based on previous experiments performed from related viruses such as SFV and SINV.
Yet it remains an expensive endeavor since the production route utilizes proton irradiations of enriched xenon-124 gas (50,000 $/l as of 2008 (Kakavand et al., 2008)) in closed systems.
The synthetic route utilized allowed for ready synthesis of 1-substituted-4-aminoimidazoles.
The new route utilized pre-existing numbered highways, including NY 175 from NY 174 in Marcellus to NY 173 in Onondaga.
One route utilizes bulk micromachining in [1 1 0] Si wafers, the other route surface micromachining with a sacrificial layer.
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