Sentence examples for the rigorous optimization from inspiring English sources

The rigorous optimization can be solved with good robustness, efficiency and reliability due to a continuous reformulation of the MINLP.

In this work, we present a methodology for the rigorous optimization of chemical processes implemented on a commercial simulator using surrogate models based on a kriging interpolation.

Compared to a single-layer architecture, the two-layer architecture is able to address control systems with complex models leading to high computational load, since the rigorous optimization problem can be solved at a slower rate than the process sampling time.

Our method not only makes the rigorous optimization-based approach applicable online but also allows the estimator to be stable and convergent.

However, there are several challenges that must be addressed when developing these multiplex immunoassays such as selection of specific antigens and antibodies, cross-reactivity, calibration, protein-reagent interferences, and the need for rigorous optimization of protein concentrations.

Furthermore, due to the exponential nature of the signal and typically the reduction of the kinetics of the signal to a single number (CT, the cycle number when sample fluorescence exceeds a chosen threshold above background fluorescence) which is used as an exponent in the estimation procedure, rigorous optimization of Q-PCR assays is especially critical.

For the most promising alternatives a rigorous optimization of the entire flowsheet is executed to determine the best alternative.

For the most promising alternatives a rigorous optimization of the entire flowsheet is consequently executed to determine the best alternative.

On the upper layer, a rigorous optimization problem is solved with an economic objective function at a slow time-scale, which captures slow trends in process uncertainties.

The advantage with mathematical programming methods is that a rigorous optimization of the structure, sizes of heat exchangers and utility usage can be carried out, whereas the designer makes these decisions if purely pinch-based tools are used.

Some of the other discrepancies could be due to lack of rigorous optimization of sensitivity parameters for the eSensor system, such as the weak HPV 54 result on reverse line blot and lack of detection on eSensor.