Defining the intended application of the biomarker (for example, will it be used for internal decision making, exploratory research, or as a diagnostic) will determine the rigor of method validation and assay documentation needed.
Given the rigor of quantitative methods and the subjective information gained through qualitative inquiry, the use of mixed methods is increasingly common in the assessment of HRQOL [ 51].
Finally, based on the rigor of the methods we followed, we trust that teachers in our interview study responded honestly to the questions asked.
Yet, until recently, it has been difficult for researchers to make definitive statements about those remains; but, as the database of discoveries has grown and the rigor of zooarchaeological methods has improved, research is revealing an ever clearer picture of the domestication of Canis familiaris.
The Warrens, for their part, are somewhat straitjacketed by the rigor of their methods.
Scientists constantly evaluate each others' work, questioning the rigor of the methods, the strength of evidence in conclusions, and looking for articulation of uncertainty.
Moreover, despite all the rigor of statistical methods, for many risk domains, such as cyber and reputation risk, the data set is shallow and largely unreported.
We believe the consistent statistical significance in both analyses demonstrates the rigor of our methods.
Inter rater reliability is adequate, lending support to the rigor of our methods.
This inconsistency is most probably due to considerable variations in the rigor of the methods used and the inadequacies of both qualitative and quantitative HRQOL assessment measures [ 1].
