The prions interfere with the glucose repression process, enabling the yeast to consume other carbon sources and slow down glucose metabolism which makes fermentation inefficient.
Further analysis of each system suggests that the observed discrepancies between in vitro and in vivo results reflect the contributions of additional equilibria to the transcription repression process.
Therefore, the co-degradation mediated by mRNA-sRNA complex is more efficiently to induce bistability than the translation repression process.
PER-dependent rhythms of CLK phosphorylation and E-box binding were shown in Drosophila, and PER-DBT (doubletime kinase) interaction is required for the transcriptional repression process.
Moreover, we observed a general repression process of metabolic pathways, specifically shown in the amino acid metabolic and lipid metabolic related pathways.
Despite our data supporting a notion that estrogen mediates epigenetic repression of the MT1 gene cluster in MCF7 cells, the underlying mechanism of what triggers this long-range coordinated repression process remains obscured.
Likewise, the heavy methylation of both LTRs in non-placenta cells supports a repression process outside placenta.
Most of the metabolism-related pathways were targeted by down-regulated genes, and a general repression process of metabolic pathways was observed.
The present experiments showed that low concentration of CdTe QDs had no obvious effect on the PCR process but excess CdTe QDs would result in the repression of PCR process, and only appropriate concentration of QDs could improve PCR specificity.
Generally, in a cellular environment, miRNAs mediate gene regulation by reducing the stability of their target mRNAs through mRNA degradation methods or using translational repression processes [ 7].
