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Exact(30)
For comparison purpose, the reported interaction energies (E int) are listed in Table 1 together with the corresponding equilibrium distances (d 0).
Overall, the data indicate a key role of the ACC in the reported interaction.
We did not investigate the reported interaction between HCN1 and protocadherin-15.
The reported interaction between LIN28B and Let-7 was recapitulated by siRNA knockdown in ovarian cancer cell lines.
The reported interaction between Grb2 and Themis1 [12] is proposed to involve both SH2 and SH3 domains of Grb2.
Our experiments reveal that Feo and Klp3A form a complex during cytokinesis and their interaction appears to be regulated by dephosphorylation (Fig 5), similar to the reported interaction between PRC1 and KIF4 in mammals [4].
Similar(30)
Similar was the case for the reported interactions with the A1R homology model in the literature (with IC50 values of 2.9 and 6.2 nM for the reported ligands predicted to bind to the homology model of A1R) [52] 52].
This uncertainty in the subcellular localization of the FBXO7 protein also complicates the interpretation of the biological plausibility of the reported interactions with other proteins.
All the reported interactions were statistically significant also on the multiplicative scale.
Future studies should therefore investigate the reported interactions in other study samples.
Most of the reported interactions for these three bacterial species come from a single high-throughput experimental study reported in Dyer et al. (2010).
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