Your English writing platform
Discover LudwigExact(6)
Furthermore, a larger percentage of the replication population had T1DM and the patients with T2DM were significantly younger.
As expected, the "conventional" model, lacking genetic factors, was not significantly associated with nephropathy in the replication population.
Our data in the replication population suggests that some factors in the model may be ethnicity, age or disease type dependent, indicating that the development of robust, highly predictive models may require specific adaptation of the models to different ethnic groups.
We found that 28.5% (310/1086 genes) of the rHH genes identified in the discovery analysis occurred in a rHH in at least one of the replication population clusters (Supplementary Table 7).
Although our findings for RUNX1 did not meet strict Bonferroni statistical significance in the replication population (NEST p > 0.00019), there were four RUNX1 CpGs in the top 100 results in the MoBa discovery population [see Supplemental Material, Table S1 (http://dx.doi.org/10.1289/ehp.1205412)].
The discovery population of 700 cases and 598 controls was assembled from Northern Han Chinese; the validation population of 586 cases and 456 controls was assembled from southern China; and the replication population of 666 cases and 701 controls was assembled from both northern and southern China.
Similar(54)
No other SNP associations remained suggestive in the replication populations.
Even though the replication of the SNP was not convincing in one of the replication populations (ICGN), the analysis in the mouse model suggests a role of SOX5 in developmental lung morphogenesis, which, as discussed, could decrease lung functional reserve in the adult.
In the NEST replication population, the direction of differential methylation in relation to maternal smoking was consistent with the direction in relation to maternal plasma cotinine for all of the 26 CpGs that were significant (p < 1.06 × 10 7) in the discovery study.
The Caucasian replication population includes asthmatic children from the GCC compared to non-asthmatic adults with no family history of asthma from the Cincinnati Control Cohort (CCC).
However, this SNP was not associated with log relative telomere length in the NHS replication population (joint P = 1.4×10−4).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com