All the synthesized compounds showed better activity than the reference standards (Doxorubicin and 5-FU).
A total of 30 camptothecin analogues, including 15 new compounds, were identified from the fruit according the fragmentation pathways of the reference standards.
The chromatographic peaks of the 16 studied compounds were successfully identified by comparing their retention time and UV spectra with the reference standards.
Surgical and histological results provided the reference standards.
The reference standards used were purchased from the company Sigma - Aldrich and / or LGC Standards s.r.l.r.l
The reference standards of the corresponding sodium salts of these organic acids were chromatographically pure (Sigma-Aldrich, Shanghai, China).
A detailed description of the reference standards is shown as Additional file 1 (document: additional information RAFT polymerization.pdf).
The retention times of the reference standards were used in detecting the pesticide residues in the extracts.
Isotope-labeled standard compounds and the reference standards were purchased by Ehrenstorfer GmbH Germany and LGC Standards Germany.
The reference standards stock solution of 1.0 mg/litre (BND 301.03) of arsenic was used prepared by NPL-India.
The phenolics were identified by comparing the retention times, UV- visible and mass spectra of unknown peaks with the reference standards.
