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In fact, the knockout of a gene sometimes has no discernible impact, whereas the reduction of expression (knockdown) of the same gene causes major defects1.
We then asked whether the reduction of expression of individual receptor subunits changes the response of WEHI 274.1 cells to BMP7.
The reduction of expression of Dlx5, Dlx6 and dHAND was invariably more pronounced in the proximal part of the 1st PA, while that of Dlx1 and Dlx2 was more evenly affected.
Our results indicate that the reduction of expression of some non-coding RNAs, in particular of MALAT-1, and SNORA60 with respect to their normal expression in prostate, as well as the upregulation of SNHG8 and SNHG1 should be monitored as useful biomarkers to track disease progression.
Second, the Gabra5−/− mouse does not limit the reduction of expression either regionally or temporally.
The reduction of expression is only found in hTERT but not in hTER of telomerase in K562 cells.
Similar(43)
It was found the reduction of expressions of Twist-1 and MMP-2, but slightly increased MMP-9, which suggested bioefficiency of the inhibitor (Fig. 1a).
Decreased CD64 expression was observed concomitant with the reduction of ISG expression after high-dose corticosteroid therapy.
These data suggest that HBSS + ebselen maintained the expression of ZO-1 and MUC16, and further prevented the reduction of p63 expression in hypothermic preservation.
Because the proteasome pathway was only partially involved in the reduction of ErbB4 expression, we examined the involvement of microRNAs (miRs) in the reduction of ErbB4 expression.
Our early studies demonstrated that the reduction of TRIM expression in TCR-modulated T cells was less severe than the reduction of CD3ε and ζ expression.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com