Sentence examples similar to the reduced half from inspiring English sources

We also identified a novel mutation where the SLE-associated 71Thr leads to the reduced half-life of BLK protein.

The reduced half-life of sororin mRNA and protein is likely to accelerate the conversion of splicing defects into a reduction of mature protein.

The authors of that finding speculate that upregulation of lamp-1 and -2 mRNA, which has been observed in various human cancers [ 148, 149], might be an attempt to compensate for the deleterious effect of the reduced half-life of LAMP-1 and -2 in cancer cells overexpressing lysosomal cysteine cathepsins.

These cells contain a mutant HIFβ subunit with a severely reduced half life and, as a consequence, they are deficient in HIF activity [26], [27].

However, this feature was only captured by the system with the reduced half-life GFP.

After CV testing, the half-wave potential of the ORR on the KB350Z-900-catalyzed electrode is negatively shifted by only 2 mV, but the reduced half-wave potential of the ORR on the JM Pt/C-catalyzed electrode is about 55 mV (Fig. 4d).

However, some potential factors may explain the reduced GH half-life in our patients with RA.

The fault led to a reduced half-hourly service between the two cities.

Defects in pre-mRNA splicing could reduce protein levels acutely especially when coupled to a reduced half-life of the corresponding mRNA and/or protein.

As the Qrr4 SL1 deletion mutant exhibited a reduced half-life, we wondered whether it is the stem-loop structure that matters or if there are specific sequences that are required for stability.

Secondly, eight of the genes affected are probably co-transcribed with TTA-containing genes, and the resulting UUA-containing mRNAs may have a reduced half-life under conditions in which the UUA codon is not readily translated.