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"the reason for this difference" is correct and usable in written English.
It can be used in a sentence to explain the cause of a variation or distinction between two things. Example: The reason for this difference in opinion is due to our contrasting cultural backgrounds.
Exact(60)
One could speculate that the reason for this difference is the different tropism of each virus.
The reason for this difference is unknown but could relate to the different expression platforms.
Deuteration effects may be the reason for this difference.
The reason for this difference is the types of studies the authors include.
The reason for this difference is that the aerobic reactors generated much more microbial products.
The reason for this difference in survival is unclear.
The reason for this difference will be discussed later.
The reason for this difference is analyzed as follows.
The reason for this difference resides in the nature of the idea of reason in question.
The reason for this difference is not entirely clear.
What is the reason for this difference?
More suggestions(15)
reasons why this difference
the causes for this difference
the cause of this difference
the reasons why this difference
the reasons for such difference
the causes of the difference
the reason for this squander
the reason for this crisis
the reason for this rush
the reason for this partnership
the reason for this ruse
the reason for this risk
the reason for this optimism
the reason for this move
the reason for this imbalance
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com