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The effect of the lipid component of PrPSc aggregates [ 41] is of particular interest, and further studies with the rapid stability assay will consider the impact of detergent treatment and lipid extraction on stability of isolates in GdnHCl.
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It is well suited for rapid stability analysis in the preliminary stage of parafoil design.
In practice, the well-known Arrhenius theory is still used to make a rapid stability prediction, to estimate a drug product shelf life during early stages of its pharmaceutical development.
Rapid stability assessment on a library scale together with novel in silico loop reconstruction and molecular dynamics simulations is demonstrated.
A simple and rapid stability-indicating reversed-phase HPLC method was developed and validated according to ICH guidelines.
A simple and rapid stability-indicating, reversed phase ultra-performance liquid chromatography (UPLC) method was developed for the quantitative determination of lafutidine and its four potential impurities.
Our method provides a powerful means for the rapid assessment of the stability of many variants, for the systematic assessment of the contribution of different factors to protein stability, and for enhancement of the protein stability.
The combination of these methods will lead to the rapid improvement of protein stability for biotechnological purposes.
HONG KONG — The Philippines received an investment-grade rating from Moody's Investors Service on Thursday, underscoring the rapid growth and political stability that the country — once seen as a "sick man of Asia" — has enjoyed in recent years.
These results suggested that the present approach is useful for the rapid evaluation of metabolic stability and structural characterization of metabolites within a short period in new drug discovery.
The simulating results show that the ASSA T can satisfy the requirements of the rapid speed attitvde maneuver and stability, as well as the energy control simultaneously.
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